Review



pituitary adenylate cyclase activating peptide 1 27  (Tocris)


Bioz Verified Symbol Tocris is a verified supplier
Bioz Manufacturer Symbol Tocris manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    Tocris pituitary adenylate cyclase activating peptide 1 27
    Pituitary Adenylate Cyclase Activating Peptide 1 27, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pituitary adenylate cyclase activating peptide 1 27/product/Tocris
    Average 93 stars, based on 8 article reviews
    pituitary adenylate cyclase activating peptide 1 27 - by Bioz Stars, 2026-03
    93/100 stars

    Images



    Similar Products

    pacap antagonist pacap 1 27  (MedChemExpress)
    93
    MedChemExpress pacap antagonist pacap 1 27
    Pacap Antagonist Pacap 1 27, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pacap antagonist pacap 1 27/product/MedChemExpress
    Average 93 stars, based on 1 article reviews
    pacap antagonist pacap 1 27 - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier
    pituitary adenylate cyclase activating peptide 1 27  (Tocris)
    93
    Tocris pituitary adenylate cyclase activating peptide 1 27
    Pituitary Adenylate Cyclase Activating Peptide 1 27, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pituitary adenylate cyclase activating peptide 1 27/product/Tocris
    Average 93 stars, based on 1 article reviews
    pituitary adenylate cyclase activating peptide 1 27 - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier
    pacap 1 27  (MedChemExpress)
    93
    MedChemExpress pacap 1 27
    Pacap 1 27, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pacap 1 27/product/MedChemExpress
    Average 93 stars, based on 1 article reviews
    pacap 1 27 - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier
    pacap  (MedChemExpress)
    92
    MedChemExpress pacap
    Pacap, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pacap/product/MedChemExpress
    Average 92 stars, based on 1 article reviews
    pacap - by Bioz Stars, 2026-03
    92/100 stars
    		  Buy from Supplier
    pacap1 27  (R&D Systems)
    93
    R&D Systems pacap1 27
    Pacap1 27, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pacap1 27/product/R&D Systems
    Average 93 stars, based on 1 article reviews
    pacap1 27 - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier
    pituitary adenylate cyclase-activating peptide (pacap) amino acids 1–27  (Bachem)
    90
    Bachem pituitary adenylate cyclase-activating peptide (pacap) amino acids 1–27
    Polarized PACAP-treated MSC maintain mesenchymal phenotype. ( A ). Immunophenotyping of PACAP-treated MSC in flow cytometry presents positive expression of the mesenchymal markers CD106 (>50%), CD29 (>80%), CD44 (>70%), CD73 (>60%) and sca-1 (>40%) but negative expression of the hematopoietic markers CD45 (<8%), and CD11b (<5%). Graphs represent flow cytometry histograms for the expression of the different markers. The negative control histogram is presented with the blue filled histogram. ( B ). Both naïve (N = 4) and PACAP-treated MSC (N = 3) expressed detectable levels of VPAC2 receptor mRNA, as detected in real-time PCR. Since the activation of Toll-like receptor 3 (TLR3) is an established marker of the MSC anti-inflammatory phenotype (MSC2) , we administered pituitary <t>adenylate</t> cyclase-activating peptide (PACAP), a neuropeptide with anti-inflammatory properties that is known to upregulate TLR3 and vice versa with TLR4, at 20 nM for 4 days to establish the anti-inflammatory MCS phenotype (MSC2). PACAP treatment of MSC in vitro (pMSC, N = 5) did not increase significantly the expression of TLR3 ( C ) or TLR4 ( D ) but increased the TLR3/TLR4 gene expression ratio ( E ) compared with naïve MSC (N = 4), as detected in real-time PCR. All graphs present mean ± SE. * p < 0.05, Student t -test. ns = non-significant.
    Pituitary Adenylate Cyclase Activating Peptide (Pacap) Amino Acids 1–27, supplied by Bachem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pituitary adenylate cyclase-activating peptide (pacap) amino acids 1–27/product/Bachem
    Average 90 stars, based on 1 article reviews
    pituitary adenylate cyclase-activating peptide (pacap) amino acids 1–27 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    hy p1023 pacap 1 27 medchemexpress  (MedChemExpress)
    93
    MedChemExpress hy p1023 pacap 1 27 medchemexpress
    Polarized PACAP-treated MSC maintain mesenchymal phenotype. ( A ). Immunophenotyping of PACAP-treated MSC in flow cytometry presents positive expression of the mesenchymal markers CD106 (>50%), CD29 (>80%), CD44 (>70%), CD73 (>60%) and sca-1 (>40%) but negative expression of the hematopoietic markers CD45 (<8%), and CD11b (<5%). Graphs represent flow cytometry histograms for the expression of the different markers. The negative control histogram is presented with the blue filled histogram. ( B ). Both naïve (N = 4) and PACAP-treated MSC (N = 3) expressed detectable levels of VPAC2 receptor mRNA, as detected in real-time PCR. Since the activation of Toll-like receptor 3 (TLR3) is an established marker of the MSC anti-inflammatory phenotype (MSC2) , we administered pituitary <t>adenylate</t> cyclase-activating peptide (PACAP), a neuropeptide with anti-inflammatory properties that is known to upregulate TLR3 and vice versa with TLR4, at 20 nM for 4 days to establish the anti-inflammatory MCS phenotype (MSC2). PACAP treatment of MSC in vitro (pMSC, N = 5) did not increase significantly the expression of TLR3 ( C ) or TLR4 ( D ) but increased the TLR3/TLR4 gene expression ratio ( E ) compared with naïve MSC (N = 4), as detected in real-time PCR. All graphs present mean ± SE. * p < 0.05, Student t -test. ns = non-significant.
    Hy P1023 Pacap 1 27 Medchemexpress, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hy p1023 pacap 1 27 medchemexpress/product/MedChemExpress
    Average 93 stars, based on 1 article reviews
    hy p1023 pacap 1 27 medchemexpress - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Polarized PACAP-treated MSC maintain mesenchymal phenotype. ( A ). Immunophenotyping of PACAP-treated MSC in flow cytometry presents positive expression of the mesenchymal markers CD106 (>50%), CD29 (>80%), CD44 (>70%), CD73 (>60%) and sca-1 (>40%) but negative expression of the hematopoietic markers CD45 (<8%), and CD11b (<5%). Graphs represent flow cytometry histograms for the expression of the different markers. The negative control histogram is presented with the blue filled histogram. ( B ). Both naïve (N = 4) and PACAP-treated MSC (N = 3) expressed detectable levels of VPAC2 receptor mRNA, as detected in real-time PCR. Since the activation of Toll-like receptor 3 (TLR3) is an established marker of the MSC anti-inflammatory phenotype (MSC2) , we administered pituitary adenylate cyclase-activating peptide (PACAP), a neuropeptide with anti-inflammatory properties that is known to upregulate TLR3 and vice versa with TLR4, at 20 nM for 4 days to establish the anti-inflammatory MCS phenotype (MSC2). PACAP treatment of MSC in vitro (pMSC, N = 5) did not increase significantly the expression of TLR3 ( C ) or TLR4 ( D ) but increased the TLR3/TLR4 gene expression ratio ( E ) compared with naïve MSC (N = 4), as detected in real-time PCR. All graphs present mean ± SE. * p < 0.05, Student t -test. ns = non-significant.

    Journal: International Journal of Molecular Sciences

    Article Title: Polarized Anti-Inflammatory Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Improve Cognitive Function in Aged Mice

    doi: 10.3390/ijms24054490

    Figure Lengend Snippet: Polarized PACAP-treated MSC maintain mesenchymal phenotype. ( A ). Immunophenotyping of PACAP-treated MSC in flow cytometry presents positive expression of the mesenchymal markers CD106 (>50%), CD29 (>80%), CD44 (>70%), CD73 (>60%) and sca-1 (>40%) but negative expression of the hematopoietic markers CD45 (<8%), and CD11b (<5%). Graphs represent flow cytometry histograms for the expression of the different markers. The negative control histogram is presented with the blue filled histogram. ( B ). Both naïve (N = 4) and PACAP-treated MSC (N = 3) expressed detectable levels of VPAC2 receptor mRNA, as detected in real-time PCR. Since the activation of Toll-like receptor 3 (TLR3) is an established marker of the MSC anti-inflammatory phenotype (MSC2) , we administered pituitary adenylate cyclase-activating peptide (PACAP), a neuropeptide with anti-inflammatory properties that is known to upregulate TLR3 and vice versa with TLR4, at 20 nM for 4 days to establish the anti-inflammatory MCS phenotype (MSC2). PACAP treatment of MSC in vitro (pMSC, N = 5) did not increase significantly the expression of TLR3 ( C ) or TLR4 ( D ) but increased the TLR3/TLR4 gene expression ratio ( E ) compared with naïve MSC (N = 4), as detected in real-time PCR. All graphs present mean ± SE. * p < 0.05, Student t -test. ns = non-significant.

    Article Snippet: Pituitary adenylate cyclase-activating peptide (PACAP) amino acids 1–27 was purchased from Bachem AG (Switzerland) cat. No. 127317-03-7.

    Techniques: Flow Cytometry, Expressing, Negative Control, Real-time Polymerase Chain Reaction, Activation Assay, Marker, In Vitro, Gene Expression